The Raman Rxn4 analyzer powered by Kaiser Raman technology is the optimal choice for manufacturing or process environments. Raman Rxn4 provides high-resolution performance for in situ, real-time measurement and control. It features unique self-monitoring, diagnostics, and self-calibration to ensure the validity of each measurement. Stackable in a standard 19" rack, the Raman Rxn4 saves valuable space on the production floor. It is also offered with an optional stainless steel NEMA 4X enclosure.
Raman downstream process measurement of biosimilars - Alvotech’s testing of the protein purification process during ultrafiltration/diafiltration (UF/DF)
By replacing offline analytical methods with Raman and tunable diode laser absorption spectroscopies, chemical processors can enhance efficiency and reliability, reduce downtime and improve safety
Boost plant safety, ensure product quality, and optimize operations. Raman spectroscopy measures the composition and molecular structure of your samples from lab-to-process in real time.
Base Model and Enclosure configuration: 150-4350 cm-1 (532 nm) 150-3425 cm-1 (785 nm) 200-2400 cm-1 (1000 nm) Hybrid: 175-1890 cm-1 (785 nm)
Spectral resolution
Base model and Enclosure configuration (average): 5 cm-1 (532 nm) 4 cm-1 (785 nm) 5 cm-1 (1000 nm) Hybrid: 4 cm-1 (785 nm) average
Channels
Base model and Enclosure configuration: Up to four channels Hybrid: Up to two channels
Temperature
Base model: Operating: 5 to 35 °C / 41 to 95 °F (532 nm, 785 nm) 5 to 30 °C / 41 to 86 °F (1000 nm) Storage: -15 to 50 °C / 5 to 122 °F Hybrid: Operating: 5 to 35 °C / 41 to 95 °F Storage: -15 to 50 °C / 5 to 122 °F Enclosure configuration: Operating: (all wavelengths) 5 to 50 °C / 41 to 122 °F Storage: -15 to 50 °C / 5 to 122 °F
Relative humidity
20 to 80 %, non-condensing
Input voltage
Base model and Hybrid: 100-240 V, 50-60 Hz, ±10% Enclosure configuration: 120 V ±10%, 60 Hz -OR- 230 V ±10%, 50/60 Hz
Power consumption (W)
Base model and Hybrid: 400 (max) 250 (typical start-up) 120 (typical running) Enclosure configuration: 1560 (max) 1560 (typical start-up) 750 (typical running)
Warm up time (minutes)
Base model and Hybrid: 120 Enclosure configuration: 240
Unit dimensions (width x height x depth)
Base model and Hybrid: 483 x 267 x 556 mm 19.02 x 10.52 x 21.89 inch Enclosure configuration: (with optional trolley) 1175 x 1480 x 826 mm 46.26 x 58.27 x 32.52 inch
Weight
Base model: 28.5 kg / 63 lbs Enclosure configuration: 185.5 kg / 409 lbs (with optional trolley)
Base model and Hybrid: 19-inch rack package Enclosure configuration: NEMA 4X enclosure; wall-mountable, moblile trolley, or fixed stand
Hazardous area certifications
Base model and Hybrid: ATEX, CSA, IECEx Enclosure configuration: Call support for options
Measuring principle
Raman spectroscopy
Spectral coverage
Base Model and Enclosure configuration: 150-4350 cm-1 (532 nm) 150-3425 cm-1 (785 nm) 200-2400 cm-1 (1000 nm) Hybrid: 175-1890 cm-1 (785 nm)
Spectral resolution
Base model and Enclosure configuration (average): 5 cm-1 (532 nm) 4 cm-1 (785 nm) 5 cm-1 (1000 nm) Hybrid: 4 cm-1 (785 nm) average
Channels
Base model and Enclosure configuration: Up to four channels Hybrid: Up to two channels
Temperature
Base model: Operating: 5 to 35 °C / 41 to 95 °F (532 nm, 785 nm) 5 to 30 °C / 41 to 86 °F (1000 nm) Storage: -15 to 50 °C / 5 to 122 °F Hybrid: Operating: 5 to 35 °C / 41 to 95 °F Storage: -15 to 50 °C / 5 to 122 °F Enclosure configuration: Operating: (all wavelengths) 5 to 50 °C / 41 to 122 °F Storage: -15 to 50 °C / 5 to 122 °F
Relative humidity
20 to 80 %, non-condensing
Input voltage
Base model and Hybrid: 100-240 V, 50-60 Hz, ±10% Enclosure configuration: 120 V ±10%, 60 Hz -OR- 230 V ±10%, 50/60 Hz
Power consumption (W)
Base model and Hybrid: 400 (max) 250 (typical start-up) 120 (typical running) Enclosure configuration: 1560 (max) 1560 (typical start-up) 750 (typical running)
Warm up time (minutes)
Base model and Hybrid: 120 Enclosure configuration: 240
Unit dimensions (width x height x depth)
Base model and Hybrid: 483 x 267 x 556 mm 19.02 x 10.52 x 21.89 inch Enclosure configuration: (with optional trolley) 1175 x 1480 x 826 mm 46.26 x 58.27 x 32.52 inch
Weight
Base model: 28.5 kg / 63 lbs Enclosure configuration: 185.5 kg / 409 lbs (with optional trolley)
Sampling probe compatibility
Base model and enclosure configuration: Raman Rxn-10 (with accessory optics) Hybrid: Channel 1 - Raman Rxn-20 (with accessory optics) Channel 2 - Raman Rxn-10 (with accessory optics)
Automation interface
OPC Modbus HTTPS (contact us for other options)
Installation options
Base model and Hybrid: 19-inch rack package Enclosure configuration: NEMA 4X enclosure; wall-mountable, moblile trolley, or fixed stand
Hazardous area certifications
Base model and Hybrid: ATEX, CSA, IECEx Enclosure configuration: Call support for options
Measuring principle
Raman spectroscopy
Spectral coverage
Base Model and Enclosure configuration: 150-4350 cm-1 (532 nm)
Spectral resolution
Base model and Enclosure configuration (average): 5 cm-1 (532 nm)
Channels
Base model and Enclosure configuration: Up to four channels
Temperature
Base model: Operating: 5 to 35 °C / 41 to 95 °F Storage: -15 to 50 °C / 5 to 122 °F Enclosure configuration: Operating: 5 to 50 °C / 41 to 122 °F Storage: -15 to 50 °C / 5 to 122 °F
Relative humidity
20 to 80 %, non-condensing
Input voltage
Base model: 100-240 V, 50-60 Hz, ±10% Enclosure configuration: 120 V ±10%, 60 Hz -OR- 230 V ±10%, 50/60 Hz
Base model and Hybrid: 483 x 267 x 556 mm 19.02 x 10.52 x 21.89 inch Enclosure configuration: (with optional trolley) 1175 x 1480 x 826 mm 46.26 x 58.27 x 32.52 inch
Weight
Base model: 28.5 kg / 63 lbs Enclosure configuration: 185.5 kg / 409 lbs (with optional trolley)
Sampling probe compatibility
Raman Rxn-10 with accessory optics Raman Rxn-40 Raman Rxn-41
Automation interface
OPC Modbus HTTPS (contact us for other options)
Installation options
Base model and Hybrid: 19-inch rack package Enclosure configuration: NEMA 4X enclosure; wall-mountable, moblile trolley, or fixed stand
Hazardous area certifications
Base model and Hybrid: ATEX, CSA, IECEx Enclosure configuration: Call support for options
Endress+Hauser - your one-source Life Sciences technology partner
PU (Publication)
English version - 06/2024
New version available in English
Graphic highlighting why Endress+Hauser is trusted by the world's top biopharmaceutical manufacturers for its Life Sciences expertise and reliable inline, real-time measurement technologies like Raman spectroscopy systems (Raman Rxn2, Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve, flow cell and flow bench, Raman optic system for single use) and liquid analysis sensor technology (Liquiline CM44P, CM442 and OUSAF44, OUSBT66 and Memosens CPS61E, CLS82E, COS81E, CLS82E).
Advanced process and product control in fermentations -
Raman spectroscopy for composition analysis in a lab
or process
PU (Publication)
English version - 03/2022
New version available in English
An overview of Raman spectroscopy analyzer systems (including the Raman Rxn2 analyzer, Raman Rxn4 analyzer, Rxn-10 probe, and Rxn-45 probe), powered by Kaiser Raman technology, for fermentation compositional analysis in a lab or process applicable to biotechnology in the food & beverage industry.
Raman analyzer application guide for the oil & gas and chemical
industries - Composition analysis of gas streams and LNG
PU (Publication)
English version - 12/2021
New version available in English
A guide to our Raman spectroscopy analyzer and probe portfolio, powered by Kaiser Raman technology, for composition analysis of gas streams and LNG (includes the Raman Rxn4 analyzer, the Raman Rxn5 analyzer, the Raman Rxn-30 probe, and Raman Rxn-41 probe) in the chemical industry and oil & gas industry.
Raman application guide for the life science industry -
Trusted composition analysis for the life sciences
PU (Publication)
English version - 04/2022
New version available in English
A guide to our Raman spectroscopy application notes for the Life Science industry (featuring the Raman Rxn2 analyzer, Raman Rxn4 analyzer, Rxn-10 probe, Rxn-20 probe, Rxn-45 probe, Rxn-46 probe, and probe accessory optics (bIO-Optic, Raman single use optic system / SUB, immersion optic, non-contact optic).
Kaiser Raman technology and Sartorius BioPAT Spectro® collaboration
Q&A - Scalable, real-time bioprocess monitoring solutions
PU (Publication)
English version - 12/2021
New version available in English
A Q&A about how our Raman spectroscopy analyzer systems (including the Raman Rxn2 analyzer, Raman Rxn4 analyzer, and Rxn-46 probe), powered by Kaiser Raman technology, integrates with the Sartorius BioPAT Spectro platform (Ambr and biostat STR) for high throughput and single use (SUB) bioprocessingin the biopharmaceutical life science industry.
Raman data library -- Faster time to market with
increased insight, productivity, and data integrity
PU (Publication)
English version - 06/2024
New version available in English
This document provides insight into the core and cGxP features of Raman data library (data organization, visualization, user management, and univariate analysis for Raman Rxn2 and Raman Rxn4 analyzers), while also addressing common questions regarding the software's functionalities.
Prioritize scalability for an efficient biopharmaceutical
product development lifecycle
PU (Publication)
Czech version - 09/2024
New version available in English
This technical paper studies the importance of scalability as a competitive advantage in bioprocessing in the Life Science industry, and Endress+Hauser's scalable Raman systems (Raman Rxn2, Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve, flow cell and flow bench, Raman optic system for single use) and liquid analysis sensor technology and Liquid Analysis portfolio (Liquiline CM44P, CM442 and OUSAF44, OUSBT66 and Memosens CPS61E, CLS82E, COS81E, CLS82E).
An overview of energy transition and the importance of gas analysis via TDLAS, QF, and Raman spectroscopy (including the J22, JT33, OXY5500, Raman Rxn4, and Raman Rxn5 analyzers) to meet the demand for an energy supply chain shift away from carbon toward renewable energy, natural gas, hydrogen, LNG, biogas and more in the oil & gas industry.
Prioritize scalability for an efficient biopharmaceutical
product development lifecycle
PU (Publication)
English version - 06/2024
New version available in English
This technical paper studies the importance of scalability as a competitive advantage in bioprocessing in the Life Science industry, and Endress+Hauser's scalable Raman systems (Raman Rxn2, Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve, flow cell and flow bench, Raman optic system for single use) and liquid analysis sensor technology and Liquid Analysis portfolio (Liquiline CM44P, CM442 and OUSAF44, OUSBT66 and Memosens CPS61E, CLS82E, COS81E, CLS82E).
Raman Rxn4 analyzer - LNG custody transfer analyzer
PU (Publication)
English version - 01/2022
New version available in English
An overview brochure about the Raman Rxn4 analyzer, a Raman spectroscopy analyzer powered by Kaiser Raman technology for LNG custody transfer in the Oil & Gas industry.
Raman calibration and verification kits - Everything needed to
calibrate and verify your Raman analyzer system for lab-to-process
scalability
PU (Publication)
English version - 12/2023
New version available in English
An overview of the Raman calibration and verification kits for the bio multi optic / single use optic and the Raman flow assembly (includes the flow bench and flow cell). These kits are to be used in conjunction with the Rxn-10 probe and Raman Rxn2 / Rxn4 analyzer for upstream and downstream bioprocessing (powered by Kaiser Raman technology).
Lab-to-process monitoring & control in Life Sciences -
Reliable measurement of bioprocess physical and
chemical properties
PU (Publication)
English version - 04/2024
New version available in English
A combined product list of analysis offerings from both Optical Analysis and LIquid Analysis for bioprocessing applications in the life science industry (including Raman Rxn2 analyzer, Raman Rxn4 analyzer, Rxn-10 probe, bio multi optic and bio sleeve, Raman flow assembly, Rxn-45 probe, Rxn-46 probe, Raman optic system for single use, Memosens CPS61E, Memosens COS81E, OUSBT66, Memosens CPS61E, Memosens CPS77E, Memosens CLS82E, OUSAF44, Memosens CPS11E, Memosens CLS16E, TOC Analyzer CA79, Liquiline transmitter platform, and Memobase software).
Endress+Hauser - your one-source Life Sciences technology partner
PU (Publication)
Czech version - 09/2024
New version available in English
Graphic highlighting why Endress+Hauser is trusted by the world's top biopharmaceutical manufacturers for its Life Sciences expertise and reliable inline, real-time measurement technologies like Raman spectroscopy systems (Raman Rxn2, Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve, flow cell and flow bench, Raman optic system for single use) and liquid analysis sensor technology (Liquiline CM44P, CM442 and OUSAF44, OUSBT66 and Memosens CPS61E, CLS82E, COS81E, CLS82E).
Raman single-use measurement precision - Real-time
composition analysis for biopharmaceutical development
and manufacturing with the Raman Rxn portfolio
Competence Brochure (CP)
English version - 08/2024
New version available in English
An eBook highlighting our Raman spectroscopy reusable and single-use bioprocessing portfolio (including the Raman Rxn2 analyzer, Raman Rxn4 analyzer, Rxn-10 probe, Rxn-46 probe, Raman single use optic system, bio multi optic, and bio sleeve), powered by Kaiser Raman technology.
