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Consistent lab-to-process measurement improves production

Smooth scale-up requires the use of similar measurement technologies from the lab to full production.

Memosens probes used in pharmaceutical lab ©Endress+Hauser

It is within the lab where various phases of drug development occur in life sciences as new drugs and therapies are discovered and developed through extensive research. Labs are then used to provide quality control monitoring as promising drugs move through process development on a pilot scale, followed by non-GMP and then GMP manufacturing.

Replacing lab-based testing with online monitoring

To ensure consistency between process and lab measurements, it is increasingly important to use measurement technologies that are as identical as possible from lab-to-process. This article examines how process and analytical instruments are used to facilitate the progression of drugs from the lab to full scale production, primarily by replacing lab-based testing with online monitoring.